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Dissection of plant Pol III transcription machinery in Arabidopsis thaliana [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
from Novagen that allows simultaneous expression in a bacterial host of up to six proteins, we have expressed together all five subunits of Arabidopsis TFIIIC. At present we can detect expression of four subunits with the exception of AtTFIIIC90...
Analysis of family 24 of the Arabidopsis thaliana J-domain chaperone proteins [abstract]
(2004)
in microbes or mammalian cells. Based upon the results of silico analyses, three proteins, atDjC43, atDjC48, and atDjC49, were assigned to Family 24. Homologous proteins are present in maize, rice, and soybean, and in a variety of animals, but none has been...
Utilization of lactate by wild-type Desulfovibrio desulfuricans strain G20 and a Cytochrome c3 mutant [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
. Using lactate and sulfate as electron donor and recipient, respectively, we have accounted for the carbon utilization and production of reducing equivalents by each strain. Results to be presented indicate that the mutation in cytochrome c3 results...
Agrobacterium tumefaciens-mediated transformation of maize (Zea mays) inbred line using a simple binary system [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
stable transformation at later culture stages, and results will be presented in poster presentation....
Behavioral assessment of mouse models of neurodegenerative disorders [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
The neuronal ceroid lipofuscinoses (NCLs) are a family of progressive hereditary neurodegenerative disorders characterized by accumulation of lysosomal storage bodies, cognitive decline, loss of motor function and premature ...
Developing an implantable optical glucose sensor for monitoring glucose concentration [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Optical biological sensors are becoming very popular for use in detecting many different kinds of analytes of interest for medical diagnostics. There are optical sensors available today to detect many things from blood ...
Science Outreach and Informal Science Education-Programs and Partnerships [abstract]
(2010-02)
by presenting scientific ideas and concepts in a lively, engaging, and accessible manner. Audiences include K-12 students and teachers, retirees, and MU students, among others. Largely through word-of-mouth, interest in SMS has grown tremendously. We have held...
Design and synthesis of biocompatible gold nanoparticles [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2005)
The design and development of nanoparticles is emerging as one of the most promising areas of science in the 21st century. Among the different types of metallic nanoparticles in present use, gold nanoparticles are intensely studied for biological...
Selective migration of neuralized mouse embryonic stem cells towards tumor cells and conditioned media [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
.05, respectively). Even though there is a decrease in the motility of the stem cells, they are more specific towards the target. Presently, we are doing immunolabeling with nestin, beta-3-tubulin, GFAP, and TuJ1 to observe the fate of the ES cells as they undergo...
Ischemia-induced increase in the expression of the regulators of G-protein signaling subtype7 (RGS7) in gerbil hippocampus [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Stroke is one of the leading causes of death in the United States. Ischemic stroke accounts for most stroke events. Transient global ischemia induced to gerbils is a well-studied animal model of neuronal death in the ...
The effects of oncogenic Ras on the ocular lenses of transgenic mice [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Ras is a small GTP-binding protein in the signal transduction pathways activated by growth factors. In
most cell types, activation of Ras is essential for normal cell proliferation. A mutation in the Ras gene
can lead ...
Effect of genistein on regulation of a phase II enzyme in human prostate cancer cell line (PC-3) [abstract]
(University of Missouri--Columbia. Office of Undergraduate Research, 2004)
Prostate cancer is an excellent candidate disease for chemo prevention because it is typically diagnosed in elderly males, therefore even a modest delay in the neoplastic development achieved through pharmacological or ...